Based on chemical, the nucleic acid extraction reagents market has been segmented into proteinase K, NaCl, CTAB/NaCl solution, chloroform/isoamyl alcohol 24:1, phenol/chloroform/isoamyl alcohol 25:24:1, isopropanol, and ethanol. Ethanol and phenol segments are expanding at a high rate, as the two reagents are easily available, price-compatible, and highly effective. Based on end-user, the nucleic acid extraction reagents market can be classified into academic research institutes, hospitals & diagnostic centers, pharmaceutical & biotechnology companies, contract research organizations (CROs), and others (such as food testing and forensic laboratories). The academic research institutes segment holds a leading share of the global market, while the hospitals & diagnostic centers segment is likely to expand at the maximum growth rate during the forecast period.
Nucleic acids are one of several macromolecules found in the body in addition to fats, proteins, and carbohydrates. A nucleic acid is a polymer composed of four nucleotides linked together in a long chain known as polynucleotide. A nucleic acid consists of DNA, RNA, and protein. The extraction and purging of nucleic acids are regularly utilized strategies to isolate genetic material from tissues, microscopic organisms, plants, and infections for imperative, explanatory, indicative, and preparative downstream procedures. Among these techniques, plasmid DNA extraction was the first to be recorded to have utilized the tedious alkaline extraction protocol.
Generally, successful refining of nucleic acids involves four important steps viz. effective disruption of cells or tissues, denaturation of nucleoprotein complexes, inactivation of nucleases (for example, RNase for RNA extraction and DNase for DNA extraction), and decontamination. The recent point-of-care diagnostics (POC-Dx) is a new approach aimed at replacement of sophisticated analytical machinery with micro-analytical systems, and able to be used near the patient, at the point of care or point of need.